16 Delicious Chicken Pasta Casserole Recipes for Weeknight Meals

Explore these delicious and easy chicken pasta casserole recipes to find a new family-favorite main dish for busy weeknights.

A chicken pasta bake is a complete, comforting meal that often needs no side dishes. Many chicken casserole and pasta bake recipes use cooked chicken breasts or leftover rotisserie or roasted chicken — a terrific way to use up leftovers. Leftover Thanksgiving turkey works well too.

Large pasta bakes are ideal for feeding a crowd or meal prepping dinners for the week. Store leftovers in an airtight container for 3–4 days. Reheat portions in the microwave in short bursts to keep the pasta moist and tasty.

Most American casseroles are baked in a 9 by 13 inch dish or an 8 by 8 inch dish. If you have the storage space, deep casserole dishes are versatile and handy. Note that casserole dishes are usually porcelain, glass, or ceramic, while baking pans are metal or tin.

Spaghetti

Fiesta Chicken Pasta Casserole Bake

This Mexican-inspired chicken pasta casserole features Rotel, sour cream, corn, black beans, green chiles, and melted cheese for a festive, flavorful bake.

Cheesy Chicken Spaghetti Casserole with Spinach

A creamy, cheesy chicken spaghetti made with rotisserie chicken, Monterey Jack and Parmesan cheeses, sour cream, spinach, and crunchy fried onions—ready in under an hour.

Chicken Spaghetti Casserole

A classic comfort bake with Rotel, Velveeta and cheddar cheeses, cream soup, aromatic seasonings, and shredded chicken—baked until golden and bubbly.

Short Pasta Shapes

Chicken Alfredo Bake

A rich, creamy Alfredo pasta bake with chicken and penne, tossed in a homemade Alfredo sauce and plenty of cheese—comfort food the whole family will love.

Chicken Fajita Pasta

A 30-minute, one-pot Tex-Mex pasta with diced bell peppers, onion, garlic, lime, and seasoned chicken for bright, bold flavors.

Baked Chicken and Broccoli Pasta

A creamy, cheesy bake featuring whole milk, heavy cream, Parmesan and mozzarella with tender chicken and broccoli florets.

Chicken Suiza Pasta Bake

Inspired by enchilada suiza, this creamy pasta bake uses milk, a Mexican cheese blend, and sour cream for a rich, comforting dish.

Baked Buffalo Chicken Pasta

A spicy, creamy bake with shredded chicken, cream cheese, hot sauce, onions, cellentani pasta, and plenty of cheese—ready in about 30 minutes.

Baked Ziti with Ground Chicken

Layers of ziti, savory ground chicken, marinara, and a trio of cheeses make this an easy, satisfying weeknight casserole.

Broccoli Chicken Casserole

A kid-friendly favorite made with broccoli florets, shredded chicken, pasta, and plenty of melted cheese.

Chicken Pasta and Veggies Casserole

An easy, veggie-packed casserole that’s perfect for picky eaters, potlucks, and busy weeknights.

Crack Chicken Pasta Bake

A crowd-pleaser made with ranch seasoning, cheddar, mozzarella, and bacon—ready in about 45 minutes.

Egg Noodles

Chicken Cordon Bleu Casserole

An indulgent casserole with layers of chicken, ham, Swiss cheese, and a creamy sauce for a rich, satisfying meal.

Chicken Noodle Casserole

A comforting bake featuring chicken, egg noodles, mixed vegetables, and a creamy sauce topped with buttery breadcrumbs.

Shells

Chicken Parmesan Stuffed Shells

A delicious mash-up of chicken Parmesan and stuffed shells, baked with cheese and marinara for a family-pleasing meal.

Chicken Alfredo Stuffed Shells

Stuffed shells filled with chicken, broccoli, spinach, mozzarella, and Parmesan in a creamy Alfredo-style sauce.

Related

Looking for more delicious pasta recipes? Try these favorites: